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Immunology

Ustekinumab

Stelara®

Ustekinumab is a fully human anti-IL-12/IL-23 monoclonal antibody. Unique dual-cytokine inhibition provides efficacy across dermatology and gastroenterology.

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Product Details

Dosage FormSC Injectable / IV Infusion
Strength45 mg/0.5mL, 90 mg/mL (SC); 130 mg/26mL (IV)
StorageStore at 2–8°C. Do not freeze or shake.
CategoryImmunology
AvailabilityAvailable for Transfer

Indication

Plaque psoriasis (moderate-to-severe); psoriatic arthritis; Crohn's disease (moderate-to-severe); ulcerative colitis (moderate-to-severe).

Mechanism of Action

Binds to the p40 subunit shared by IL-12 and IL-23, preventing their interaction with IL-12Rβ1 on T cells and NK cells. Inhibits Th1 and Th17 inflammatory pathways.

Technology Transfer Package

Each Burrard Pharmaceuticals technology transfer package for Ustekinumab includes comprehensive documentation and support:

Master Formula

Complete formulation with manufacturing parameters, excipient specifications, and process controls.

Analytical Methods

Validated methods for assay, impurities, dissolution, and stability-indicating analysis.

CTD/eCTD Templates

Market-ready regulatory dossier templates — available through Burrard Intelligence subscription.

Stability Data

ICH-compliant stability studies (accelerated and long-term) with detailed protocols.

Manufacturing Protocols

Scale-up procedures, batch records, equipment specifications, and in-process controls.

Expert Support

Direct advisory access to formulation scientists and regulatory specialists throughout transfer.

Ready for Ustekinumab Technology Transfer?

Our team can deliver the complete know-how package within 2–21 business days. Book a consultation to discuss your specific requirements.

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