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Oncology

Trastuzumab

Herceptin®

Trastuzumab is a humanized monoclonal antibody targeting the HER2 receptor. Used in HER2-positive breast cancer and gastric cancer.

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Product Details

Dosage FormIV Injectable (Lyophilized Powder)
Strength150 mg, 440 mg vials
StorageStore at 2–8°C. Reconstituted solution stable for 28 days at 2–8°C.
CategoryOncology
AvailabilityAvailable for Transfer

Indication

HER2-overexpressing breast cancer (adjuvant, metastatic); HER2-overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.

Mechanism of Action

Binds to subdomain IV of the extracellular domain of HER2, inhibiting receptor dimerization, signaling, and promoting antibody-dependent cell-mediated cytotoxicity (ADCC).

Technology Transfer Package

Each Burrard Pharmaceuticals technology transfer package for Trastuzumab includes comprehensive documentation and support:

Master Formula

Complete formulation with manufacturing parameters, excipient specifications, and process controls.

Analytical Methods

Validated methods for assay, impurities, dissolution, and stability-indicating analysis.

CTD/eCTD Templates

Market-ready regulatory dossier templates — available through Burrard Intelligence subscription.

Stability Data

ICH-compliant stability studies (accelerated and long-term) with detailed protocols.

Manufacturing Protocols

Scale-up procedures, batch records, equipment specifications, and in-process controls.

Expert Support

Direct advisory access to formulation scientists and regulatory specialists throughout transfer.

Ready for Trastuzumab Technology Transfer?

Our team can deliver the complete know-how package within 2–21 business days. Book a consultation to discuss your specific requirements.

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