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Oncology

Pembrolizumab

Keytruda®

Pembrolizumab is a humanized anti-PD-1 monoclonal antibody. It blocks the PD-1/PD-L1 pathway, reactivating the immune response against tumor cells.

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Product Details

Dosage FormIV Injectable (Solution / Lyophilized Powder)
Strength25 mg/mL; 100 mg/4mL vial
StorageStore at 2–8°C. Do not freeze.
CategoryOncology
AvailabilityAvailable for Transfer

Indication

Melanoma; NSCLC; HNSCC; classical Hodgkin lymphoma; urothelial carcinoma; MSI-H/dMMR cancers; gastric cancer; cervical cancer; hepatocellular carcinoma.

Mechanism of Action

Binds to PD-1 receptor on T cells, blocking interaction with PD-L1/PD-L2 ligands on tumor cells. This releases PD-1 pathway-mediated inhibition of immune response against tumors.

Technology Transfer Package

Each Burrard Pharmaceuticals technology transfer package for Pembrolizumab includes comprehensive documentation and support:

Master Formula

Complete formulation with manufacturing parameters, excipient specifications, and process controls.

Analytical Methods

Validated methods for assay, impurities, dissolution, and stability-indicating analysis.

CTD/eCTD Templates

Market-ready regulatory dossier templates — available through Burrard Intelligence subscription.

Stability Data

ICH-compliant stability studies (accelerated and long-term) with detailed protocols.

Manufacturing Protocols

Scale-up procedures, batch records, equipment specifications, and in-process controls.

Expert Support

Direct advisory access to formulation scientists and regulatory specialists throughout transfer.

Ready for Pembrolizumab Technology Transfer?

Our team can deliver the complete know-how package within 2–21 business days. Book a consultation to discuss your specific requirements.

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