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Ophthalmics

Nepafenac

Nevanac®

Nepafenac is a prodrug NSAID that is bioactivated in ocular tissues. Used for pain and inflammation associated with cataract surgery.

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Product Details

Dosage FormOphthalmic Suspension
Strength0.1%, 0.3%
StorageStore at 2–25°C.
CategoryOphthalmics
AvailabilityAvailable for Transfer

Indication

Postoperative pain and inflammation associated with cataract surgery; prevention of macular edema after cataract surgery in diabetic patients.

Mechanism of Action

Prodrug rapidly converted by intraocular hydrolases to amfenac, a potent COX inhibitor. Bioactivation within the eye provides targeted anti-inflammatory activity with reduced systemic exposure.

Technology Transfer Package

Each Burrard Pharmaceuticals technology transfer package for Nepafenac includes comprehensive documentation and support:

Master Formula

Complete formulation with manufacturing parameters, excipient specifications, and process controls.

Analytical Methods

Validated methods for assay, impurities, dissolution, and stability-indicating analysis.

CTD/eCTD Templates

Market-ready regulatory dossier templates — available through Burrard Intelligence subscription.

Stability Data

ICH-compliant stability studies (accelerated and long-term) with detailed protocols.

Manufacturing Protocols

Scale-up procedures, batch records, equipment specifications, and in-process controls.

Expert Support

Direct advisory access to formulation scientists and regulatory specialists throughout transfer.

Ready for Nepafenac Technology Transfer?

Our team can deliver the complete know-how package within 2–21 business days. Book a consultation to discuss your specific requirements.

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