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Cardiovascular

Metoprolol

Lopressor® / Toprol-XL®

Metoprolol is a selective beta-1 adrenergic blocker used for hypertension, angina, heart failure, and acute MI.

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Product Details

Dosage FormOral Tablet (Immediate/Extended-Release) / IV Injectable
Strength25 mg, 50 mg, 100 mg, 200 mg (oral); 1 mg/mL (IV)
StorageStore at 25°C. Protect from moisture and light.
CategoryCardiovascular
AvailabilityAvailable for Transfer

Indication

Hypertension; angina pectoris; heart failure (stable NYHA II-III); acute MI; rate control in atrial fibrillation.

Mechanism of Action

Selective beta-1 adrenergic receptor antagonist that reduces heart rate, cardiac output, and myocardial oxygen demand. At higher doses may also block beta-2 receptors.

Technology Transfer Package

Each Burrard Pharmaceuticals technology transfer package for Metoprolol includes comprehensive documentation and support:

Master Formula

Complete formulation with manufacturing parameters, excipient specifications, and process controls.

Analytical Methods

Validated methods for assay, impurities, dissolution, and stability-indicating analysis.

CTD/eCTD Templates

Market-ready regulatory dossier templates — available through Burrard Intelligence subscription.

Stability Data

ICH-compliant stability studies (accelerated and long-term) with detailed protocols.

Manufacturing Protocols

Scale-up procedures, batch records, equipment specifications, and in-process controls.

Expert Support

Direct advisory access to formulation scientists and regulatory specialists throughout transfer.

Ready for Metoprolol Technology Transfer?

Our team can deliver the complete know-how package within 2–21 business days. Book a consultation to discuss your specific requirements.

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