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Oncology

Etoposide

VePesid® / Toposar®

Etoposide is a topoisomerase II inhibitor derived from podophyllotoxin. Used in small cell lung cancer, testicular cancer, and lymphomas.

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Product Details

Dosage FormIV Injectable (Solution) / Oral Capsule
Strength20 mg/mL (IV); 50 mg capsules
StorageStore at 20–25°C. Diluted solution stable for 96 hours at 25°C.
CategoryOncology
AvailabilityAvailable for Transfer

Indication

Refractory testicular tumors (with other agents); small cell lung cancer (first-line with cisplatin).

Mechanism of Action

Forms a complex with topoisomerase II and DNA, preventing DNA religation and causing double-strand breaks that trigger apoptosis.

Technology Transfer Package

Each Burrard Pharmaceuticals technology transfer package for Etoposide includes comprehensive documentation and support:

Master Formula

Complete formulation with manufacturing parameters, excipient specifications, and process controls.

Analytical Methods

Validated methods for assay, impurities, dissolution, and stability-indicating analysis.

CTD/eCTD Templates

Market-ready regulatory dossier templates — available through Burrard Intelligence subscription.

Stability Data

ICH-compliant stability studies (accelerated and long-term) with detailed protocols.

Manufacturing Protocols

Scale-up procedures, batch records, equipment specifications, and in-process controls.

Expert Support

Direct advisory access to formulation scientists and regulatory specialists throughout transfer.

Ready for Etoposide Technology Transfer?

Our team can deliver the complete know-how package within 2–21 business days. Book a consultation to discuss your specific requirements.

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