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Cardiovascular

Alirocumab

Praluent®

Alirocumab is a PCSK9 inhibitor for patients with hypercholesterolemia who cannot achieve adequate LDL-C reduction with statins alone.

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Product Details

Dosage FormSC Injectable (Prefilled Pen / Syringe)
Strength75 mg/mL, 150 mg/mL
StorageStore at 2–8°C. May store at room temperature (up to 25°C) for up to 30 days.
CategoryCardiovascular
AvailabilityAvailable for Transfer

Indication

HeFH; clinical ASCVD requiring additional LDL-C lowering; statin intolerance.

Mechanism of Action

Fully human IgG1 monoclonal antibody that binds to PCSK9, inhibiting PCSK9 binding to LDL receptors and increasing LDL receptor recycling and LDL-C clearance.

Technology Transfer Package

Each Burrard Pharmaceuticals technology transfer package for Alirocumab includes comprehensive documentation and support:

Master Formula

Complete formulation with manufacturing parameters, excipient specifications, and process controls.

Analytical Methods

Validated methods for assay, impurities, dissolution, and stability-indicating analysis.

CTD/eCTD Templates

Market-ready regulatory dossier templates — available through Burrard Intelligence subscription.

Stability Data

ICH-compliant stability studies (accelerated and long-term) with detailed protocols.

Manufacturing Protocols

Scale-up procedures, batch records, equipment specifications, and in-process controls.

Expert Support

Direct advisory access to formulation scientists and regulatory specialists throughout transfer.

Ready for Alirocumab Technology Transfer?

Our team can deliver the complete know-how package within 2–21 business days. Book a consultation to discuss your specific requirements.

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